China wholesale 148-24-3 - 4-Chloro-4’-Hydroxy Benzophenone,CAS#42019-78-3 – MEVA
China wholesale 148-24-3 - 4-Chloro-4’-Hydroxy Benzophenone,CAS#42019-78-3 – MEVA Detail:
Specification:
Appearance: Orange to brick red crystal powder
Loss on drying: ≤0.50%
Residue on ignition: ≤0.5%
Single impurity: ≤0.5%
Total impurities: ≤1.5%
Purity: ≥99.0%
Packing: 250kg/bag and 25kg/fiber drum
Physicochemical properties:
Density: 1.307 g / cm3
Melting point: 177-181 ° C
Flash point: 100 ° C
Refractive index: 1.623
Storage condition: store in a tightly closed container Store in a cool, dry, well-ventilated area away from incompatible substances.
Stable: Stable under normal temperatures and pressures
Specific application
It is generally used in organic synthesis and is an intermediate of the anti infertility drug radiomiphene
Production method:
1. P-chlorobenzoyl chloride was prepared by the reaction of p-chlorobenzoyl chloride with anisole, followed by hydrolysis and demethylation.
2. Reaction of p-chlorobenzoyl chloride with phenol: dissolve 9.4g (0.1mol) of phenol in 4ml of 10% sodium hydroxide solution, add 14ml (0.110mol) of p-chlorobenzoyl chloride dropwise at 40 ~ 45 ℃, add it within 30min, and react at the same temperature for 1H. Cool to room temperature, filter and dry to obtain 22.3g of phenyl p-Chlorobenzoate. The yield is 96%, and the melting point is 99 ~ 101 ℃.
Production method:
1. P-chlorobenzoyl chloride was prepared by the reaction of p-chlorobenzoyl chloride with anisole, followed by hydrolysis and demethylation.
2. Reaction of p-chlorobenzoyl chloride with phenol: dissolve 9.4g (0.1mol) of phenol in 4ml of 10% sodium hydroxide solution, add 14ml (0.110mol) of p-chlorobenzoyl chloride dropwise at 40 ~ 45 ℃, add it within 30min, and react at the same temperature for 1H. Cool to room temperature, filter and dry to obtain 22.3g of phenyl p-Chlorobenzoate. The yield is 96%, and the melting point is 99 ~ 101 ℃.
Health hazard:
cause skin irritation. Cause serious eye irritation. May cause respiratory tract irritation.
Precautions:
Clean thoroughly after operation.
Wear protective gloves / protective clothing / protective goggles / protective masks.
Avoid inhalation of dust / smoke / gas / smoke / vapour / spray.
Use only outdoors or with good ventilation.
Accident response:
In case of skin contamination: wash thoroughly with water.
In case of skin irritation: seek medical attention.
Take off the contaminated clothes and wash them before reuse
If in eyes: Rinse carefully with water for a few minutes. If you wear contact lenses and can easily take them out, take them out. Continue flushing.
If you still feel eye irritation: see a doctor / doctor.
In case of accidental inhalation: transfer the person to a place with fresh air and maintain a comfortable breathing position.
If you feel unwell, call the detoxification center / doctor
Safe storage:
Store in a well ventilated place. Keep the container closed.
The storage area must be locked.
Waste disposal:
Dispose of contents / containers in accordance with local regulations.
First aid measures:
Inhalation: if inhaled, move the patient to fresh air.
Skin contact: take off contaminated clothes and wash skin thoroughly with soapy water and clear water. If you feel unwell, see a doctor.
Eye contact: separate eyelids and rinse with flowing water or normal saline. Seek medical attention immediately.
Ingestion: gargle and do not induce vomiting. Seek medical attention immediately.
Advice to protect the rescuer: transfer the patient to a safe place. Consult a doctor. Show this chemical safety technical manual to the doctor on site.
Product detail pictures:
Related Product Guide:
It is actually our accountability to satisfy your needs and effectively serve you. Your pleasure is our best reward. We're on the lookout forward for your stop by for joint growth for China wholesale 148-24-3 - 4-Chloro-4’-Hydroxy Benzophenone,CAS#42019-78-3 – MEVA , The product will supply to all over the world, such as: South Korea, Algeria, Lithuania, We have our own registered brand and our company is developing rapidly owing to high quality products, competitive price and excellent service. We sincerely hope to establish business relations with more friends from home and abroad in the near future. We look forward to your correspondence.
By Chloe from Portugal - 2018.09.23 18:44
The customer service reprersentative explained very detailed, service attitude is very good, reply is very timely and comprehensive, a happy communication! We hope to have a opportunity to cooperate.
By Denise from Morocco - 2018.06.05 13:10